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Clinical Psychopharmacology for the Busy Practitioner

All right. I can’t read that word. ‘Clinical Psycho-pharmacology For The Busy Practitioner’, by Hugo Rosen, whatever. All right. So what do we got in here? Oh, wow. So, if you want to know all about drugs, psychiatric assessment, antidepressant drugs, mood stabilizing drugs. A lot, oh. The violent patient, the suicidal patient, geriatrics, psycho-pharmacological medical diseases that mimic psychotic disorders, treatment of drug abuse, alcoholism, psychoactive drug interactions, anti-anxiety and hypnotic drugs, anti-psychotic or neuroleptic drugs. Man, this got a whole, I mean, this is, literally like it says, this is the psycho-pharmacology for the busy practitioner. So it got it all, right down, for you. So let’s go to, what does he talk about?

So, antidepressant drugs, right? In today’s world, a lot of people on it, especially in America. I think it was something ridiculous as 50%, of America, is on some type of pill, right? One of these drugs. All right. Well, these are the categories, but … This is just ridiculous. I mean, he really goes into this. Wow. Yeah, I’m just reading and, man, it’s really going through, in detail, drugs that block alderlene, I don’t know how to pronounce half the stuff. Basic [inaudible 00:02:51], ethanol, metabolism levels, alcohol levels in non tolerant drinker, science in alcohol, or drug, abuse. We got drugs and medical illness that may and induce depression in the elderly patient. The most common psychiatric symptoms of endocrine diseases, opiate withdrawals, important neuropeptides, after, I’ll probably still never be able to pronounce these words, but I’ll be able to give you a better explanation of what they are, right? So let’s go to anti-psychotic. I’m more interested in that than mood stabilizers or antidepressants, 103.

Anti-psychotic. In 1952, demonstrated the efficiency of chlorpromazine in acute psychosis. At present, there are several anti-psychotic drugs, AP, of element United States. What is this, AP stands for? Excuse me. AP, anti-psychotic, neuroleptic drugs. I don’t know if you’ve already received that. If you weren’t, I apologize. In the United States, [inaudible 00:04:29] on all are effective by acting on the [inaudible 00:04:32] Darale system, except Klonopin, induce pseudo Parkinson’s. It is believed that AP, [inaudible 00:04:49] schizophrenia by acting on mesolimbic, or, yeah wow. You probably can’t understand anything that I’m saying either, so I’m not going to keep badgering these long words, right? You can read the report and then you can pretend that you know what you’re talking about. I can see the words and make sense, but, I know I’ve heard of. I know that’s how you spelled it though. All right.

Okay, here we go. All AP have been found to be more effective than a placebo, in both acute and chronic schizophrenics. About 75 of schizophrenics respond to AP, as compared with only 25 on a placebo. When an AP were used in maintenance therapy, one half of schizophrenics relapsed over a two year follow-up period. However, 85% of the placebo treated patients relapse over the same period. Therefore, AP are more effective than the placebo, but many patients relapse despite adequate treatment. There are no overall differences in clinical efficiency among the AP drugs. They do differ in their side effects, doses and formulations. Okay, wow. And then it goes, the frequently prescribed anti-psychotic drugs … My goodness. Okay, positive and negative symptoms of schizophrenia. I’m not going to go too much because I’m going to have to read a lot, because this is really brand new. I mean, it’s quite interesting. Once I go through, once I accept the fact I don’t know half the words they’re talking about, and once it’s okay that you don’t know the words, and you know, you just see the word over and over again, you know it’s important, right? Wow. How many bloody things are there?

So this is way more intense. You see I’m still flipping over here. Side effects of anti-psychotic drugs, early onset early onset, other side effects. Yeah. Skin rashes, a whole bunch of late onset whoa, rabbit syndrome. What is the rabbit syndrome? Just because you know, rabbit syndrome is a possible late Parkinson’s variant.